Magnesium matters. Here’s why:

• 7 out of 10 Americans are below the Dietary Reference Intake for Magnesium, according to a USDA Agricultural Research Report¹
  
• Sufficient magnesium intake is important in helping to*:
  • maintain the function of the heart, muscles, and nervous system
  • support learning and memory performance in aging adults
  • absorb and utilize potassium and calcium properly
• Magnesium is also critical for athletes’ endurance in order to help maintain electrolyte and energy levels.^* To learn more about the impact of adequate magnesium intake among athletes, click here.
  

  Do you lose energy and feel that you are working harder than you should to maintain your pace?

  Studies have shown that decreased levels of magnesium cause the body to use more oxygen and energy during workouts.¹

  Did you know that long distance or endurance athletes need to pay attention to magnesium intake?

  Researchers have confirmed that serum and urinary magnesium concentrations decrease significantly while running a marathon, enough to produce magnesium deficiency.²

  Did you know that sweating can drain magnesium from your body?

  As with many of the important electrolytes, runners lose magnesium when they sweat. Sweating heavily drains magnesium and other electrolytes to a point that can interfere with important functions in the body.¹

  *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  1. Lukaski HC. Magnesium, zinc, and chromium nutriture and physical activity. Am J Clin Nutr.2000;72(2 Suppl):585S-593S.
  2. Buchman Al, et al. “The effect of a marathon run on plasma and urine mineral and metal concentrations.” Journal of the American Colege of Nutrition, 1998; 17(2):124-127.

• Adults with certain health concerns or who are taking medication may need magnesium supplementation. Magnesium can be found in foods such as green and leafy vegetables, halibut, nuts, such as almonds, and sunflower seeds and in a high-quality dietary supplement such as SlowMag Mg.^2-12 To see what your Reference Daily Intake (RDI) of Magnesium is, click here.¹³

• Click here to learn more about medical conditions which may be associated with magnesium loss.
  

  Medical conditions which may be associated with magnesium loss^1-5, ¹⁰

  Gastrointestinal Loss

  • Extensive bowel resection
  • Intestinal or biliary fistulas
  • Celiac disease
  • Ulcerative colitis
  • Crohn’s Disease
  • Chronic/excessive diarrhea/vomiting

  Renal Causes

  • Chronic pyelonephritis
  • Postobstructive nephropathy

  Inherited Disorders

  • Gitelman’s syndrome (hypocalcemia and hypomagnesemia)
  • Bartter’s syndrome

  Endocrine

  • Hyperaldosteronism
  • Hyperthyroidism
  • Hyperparathyroidism
  • Poorly controlled diabetes mellitus

  Nutritional

  • Alcoholism and alcohol cirrhosis
  • Protein and calorie malnutrition
  • Prolonged parenteral fluid without magnesium

  References
  1. Whang R, Hampton EM, Whang DD. Magnesium homeostasis and clinical disorders of magnesium deficiency. Ann Pharmacother. 1994;28(2): 220-226.

  2. Maher TJ. Medications, alcohol consumption and magnesium: ensuring adequate intake of oral magnesium. The Magnesium Report Clinical, Research, and Laboratory News for Cardiologists. Second Quarter 2000. Available at: http://www.mgwater.com/adequate.shtml Accessed 6/4/2014.

  3. National Institutes of Health, Office of Dietary Supplements. Available at: http://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/. Accessed 05/2014.

  4. Dipalma JR. Magnesium Replacement Therapy. Am Fam Physician. 1990;42(1):173-176.

  5. Martin KJ, Gonzalez EA, Slatopolsky E. Clinical consequences and management of hypomagnesemia. J Am Soc Nephrol. 2009;20(11):2291-2295.

  6. Cundy T, Mackay J. Proton pump inhibitors and severe hypomagnesaemia. Curr Opin Gastroenterol .2011; 27: 180–185.

  7. O’Neill LW, Culpepper BL, Galdo JA. Long-term consequences of chronic proton pump inhibitor use. US Pharm. 2011;27:180–185.

  8. US Department of Health and Human Services, Drug Safety Communication. FDA Drug Safety Communication: Low magnesium levels can be associated with long-term use of proton pump inhibitor drugs (PPIs). 03 March 2011; Available at: http://www.fda.gov/drugs/drugsafety/ucm245011.htm. Accessed 06/4/2014.

  9. Izzedine H, Bahleda R, Khayat D, et al. Electrolyte disorders related to EGFR-targeted drugs. Crit Rev Oncol Hematol. 2010; 73(3): 213-219.

  10. Saif MW. Management of hypomagnesemia in cancer patients receiving chemotherapy. J Support Oncol. 2008;6: 243-248.

  11. Atsmon J, Dolev E. Drug-induced hypomagnesaemia. Drug Saf.2005;28(9):763-788.